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De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma
Glioblastoma is a primary brain cancer with a near 100% recurrence rate. Upon recurrence, the tumour is resistant to all conventional therapies, and because of this, 5-year survival is dismal. One of the major drivers of this high recurrence rate is the ability of glioblastoma cells to adapt to comp...
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| Publicado no: | Brain |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8105035/ https://ncbi.nlm.nih.gov/pubmed/33855339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awab020 |
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