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Differential requirement of NPHP1 for compartmentalized protein localization during photoreceptor outer segment development and maintenance

Nephrocystin (NPHP1) is a ciliary transition zone protein and its ablation causes nephronophthisis (NPHP) with partially penetrant retinal dystrophy. However, the precise requirements of NPHP1 in photoreceptors are not well understood. Here, we characterize retinal degeneration in a mouse model of N...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Datta, Poppy, Cribbs, J. Thomas, Seo, Seongjin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8104407/
https://ncbi.nlm.nih.gov/pubmed/33961633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246358
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