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Characterization of aminobenzylphenols as protein disulfide isomerase inhibitors in glioblastoma cell lines
Disulfide bond formation is a critical post−translational modification of newly synthesized polypeptides in the oxidizing environment of the endoplasmic reticulum and is mediated by protein disulfide isomerase (PDIA1). In this study, we report a series of α-aminobenzylphenol analogues as potent PDI...
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| Vydáno v: | J Med Chem |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8103808/ https://ncbi.nlm.nih.gov/pubmed/32830969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c00728 |
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