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Viral-Mediated Tethering to SEL1L Facilitates Endoplasmic Reticulum-Associated Degradation of IRE1

The unfolded protein response (UPR) and endoplasmic reticulum (ER)-associated degradation (ERAD) are two essential components of the quality control system for proteins in the secretory pathway. When unfolded proteins accumulate in the ER, UPR sensors such as inositol-requiring enzyme 1 (IRE1) induc...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hinte, Florian, Müller, Jendrik, Brune, Wolfram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103693/
https://ncbi.nlm.nih.gov/pubmed/33472927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01990-20
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