Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival

Suppressor/Enhancer of Lin-12-like (Sel1L) is an adaptor protein for the E3 ligase hydroxymethylglutaryl reductase degradation protein 1 (Hrd1) involved in endoplasmic reticulum-associated degradation (ERAD). Sel1L’s physiological importance in mammalian ERAD, however, remains to be established. Her...

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Main Authors: Sun, Shengyi, Shi, Guojun, Han, Xuemei, Francisco, Adam B., Ji, Yewei, Mendonça, Nuno, Liu, Xiaojing, Locasale, Jason W., Simpson, Kenneth W., Duhamel, Gerald E., Kersten, Sander, Yates, John R., Long, Qiaoming, Qi, Ling
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2014
Ábhair:
PNAS Plus
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918815/
https://ncbi.nlm.nih.gov/pubmed/24453213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318114111
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