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Using Split Luciferase Assay and Anti-Herpes Simplex Virus Glycoprotein Monoclonal Antibodies To Predict a Functional Binding Site between gD and gH/gL
Herpes simplex virus (HSV) entry and cell-cell fusion require glycoproteins gD, gH/gL, and gB. HSV entry begins with gD binding its receptor (nectin-1), which then activates gH/gL to enable the conversion of prefusion gB to its active form to promote membrane fusion. Virus-neutralizing monoclonal an...
Gorde:
| Argitaratua izan da: | J Virol |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Microbiology
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8103690/ https://ncbi.nlm.nih.gov/pubmed/33504603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00053-21 |
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