Using Antibodies and Mutants To Localize the Presumptive gH/gL Binding Site on Herpes Simplex Virus gD

HSV virus-cell and cell-cell fusion requires multiple interactions between four essential virion envelope glycoproteins, gD, gB, gH, and gL, and between gD and a cellular receptor, nectin-1 or herpesvirus entry mediator (HVEM). Current models suggest that binding of gD to receptors induces a conform...

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Publicat a:J Virol
Autors principals: Atanasiu, Doina, Saw, Wan Ting, Lazear, Eric, Whitbeck, J. Charles, Cairns, Tina M., Lou, Huan, Eisenberg, Roselyn J., Cohen, Gary H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258950/
https://ncbi.nlm.nih.gov/pubmed/30282715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01694-18
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