Using Antibodies and Mutants To Localize the Presumptive gH/gL Binding Site on Herpes Simplex Virus gD

HSV virus-cell and cell-cell fusion requires multiple interactions between four essential virion envelope glycoproteins, gD, gB, gH, and gL, and between gD and a cellular receptor, nectin-1 or herpesvirus entry mediator (HVEM). Current models suggest that binding of gD to receptors induces a conform...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Atanasiu, Doina, Saw, Wan Ting, Lazear, Eric, Whitbeck, J. Charles, Cairns, Tina M., Lou, Huan, Eisenberg, Roselyn J., Cohen, Gary H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258950/
https://ncbi.nlm.nih.gov/pubmed/30282715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01694-18
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