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Surface Plasmon Resonance Reveals Direct Binding of Herpes Simplex Virus Glycoproteins gH/gL to gD and Locates a gH/gL Binding Site on gD
Herpes simplex virus (HSV) requires fusion between the viral envelope and host membrane. Four glycoproteins, gD, gH/gL, and gB, are essential for this process. To initiate fusion, gD binds its receptor and undergoes a conformational change that hypothetically leads to activation of gH/gL, which in t...
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Publicado en: | J Virol |
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Autores principales: | , , , , , , , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6639271/ https://ncbi.nlm.nih.gov/pubmed/31092568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00289-19 |
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