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Selective Disruption of SERINC5 Antagonism by Nef Impairs Simian Immunodeficiency Virus Replication in Primary CD4(+) T Cells
The Nef proteins of human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) enhance viral infectivity by preventing the incorporation of the multipass transmembrane protein serine incorporator 5 (SERINC5) and, to a lesser extent, SERINC3 into virions. In addition to count...
Shranjeno v:
| izdano v: | J Virol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8103682/ https://ncbi.nlm.nih.gov/pubmed/33504599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01911-20 |
| Oznake: |
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