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Selective Disruption of SERINC5 Antagonism by Nef Impairs Simian Immunodeficiency Virus Replication in Primary CD4(+) T Cells

The Nef proteins of human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) enhance viral infectivity by preventing the incorporation of the multipass transmembrane protein serine incorporator 5 (SERINC5) and, to a lesser extent, SERINC3 into virions. In addition to count...

詳細記述

保存先:
書誌詳細
出版年:J Virol
主要な著者: Janaka, Sanath Kumar, Palumbo, Alexandra V., Tavakoli-Tameh, Aidin, Evans, David T.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103682/
https://ncbi.nlm.nih.gov/pubmed/33504599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01911-20
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