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Resident memory T cells form during persistent antigen exposure leading to allograft rejection

Tissue resident memory T cells (T(RM)) contained at sites of previous infection provide local protection against re-infection. Whether they form and function in organ transplants where cognate antigen persists is unclear. This is a key question in transplantation as T cells are detected long-term in...

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Bibliografski detalji
Izdano u:Sci Immunol
Glavni autori: Abou-Daya, Khodor I., Tieu, Roger, Zhao, Daqiang, Rammal, Rayan, Sacirbegovic, Faruk, Williams, Amanda L., Shlomchik, Warren D., Oberbarnscheidt, Martin H., Lakkis, Fadi G.
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103522/
https://ncbi.nlm.nih.gov/pubmed/33741656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abc8122
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