Cross-dressed dendritic cells sustain effector T cell responses in islet and kidney allografts

Activation of host T cells that mediate allograft rejection is a 2-step process. The first occurs in secondary lymphoid organs where T cells encounter alloantigens presented by host DCs and differentiate to effectors. Antigen presentation at these sites occurs principally via transfer of intact, don...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Hughes, Andrew D., Zhao, Daqiang, Dai, Hehua, Abou-Daya, Khodor I., Tieu, Roger, Rammal, Rayan, Williams, Amanda L., Landsittel, Douglas P., Shlomchik, Warren D., Morelli, Adrian E., Oberbarnscheidt, Martin H., Lakkis, Fadi G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934226/
https://ncbi.nlm.nih.gov/pubmed/31763998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125773
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