טוען...

Ketoconazole and Posaconazole Selectively Target HK2-expressing Glioblastoma Cells

PURPOSE: Hexokinase II (HK2) protein expression is elevated in glioblastoma (GBM), and we have shown that HK2 could serve as an effective therapeutic target for GBM. Here, we interrogated compounds that target HK2 effectively and restrict tumor growth in cell lines, patient-derived glioma stem cells...

תיאור מלא

שמור ב:

מידע ביבליוגרפי
הוצא לאור ב:	Clin Cancer Res
Main Authors:	Agnihotri, Sameer, Mansouri, Sheila, Burrell, Kelly, Li, Mira, Mamatjan, Yasin, Liu, Jeff, Nejad, Romina, Kumar, Sushil, Jalali, Shahrzad, Singh, Sanjay K., Vartanian, Alenoush, Chen, Eric Xueyu, Karimi, Shirin, Singh, Olivia, Bunda, Severa, Mansouri, Alireza, Aldape, Kenneth D., Zadeh, Gelareh
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	2018
נושאים:	Article
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC8103287/ https://ncbi.nlm.nih.gov/pubmed/30322879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-1854
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

Ketoconazole and Posaconazole Selectively Target HK2-expressing Glioblastoma Cells

פריטים דומים