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TM-10 ALTERATIONS IN METABOLIC PATHWAYS IN GLIOBLASTOMA MULTIFORME CELLS IN RESPONSE TO HEXOKINASE-2 INHIBITION

INTRODUCTION: GBMs are characterized by elevated glycolysis, however to date effective therapies targeting tumor glycolysis have not been identified. Also, the contribution of metabolic pathways other than glycolysis, such as glutamine and fatty acid oxidation, that are key in providing carbon to TC...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Kumar, Sushil, Jalali, Shahrzad, Vartanian, Alenoush, Agnihotri, Sameer, Burrell, Kelly, Zadeh, Gelareh
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218620/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou278.10
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