TM-10 ALTERATIONS IN METABOLIC PATHWAYS IN GLIOBLASTOMA MULTIFORME CELLS IN RESPONSE TO HEXOKINASE-2 INHIBITION

INTRODUCTION: GBMs are characterized by elevated glycolysis, however to date effective therapies targeting tumor glycolysis have not been identified. Also, the contribution of metabolic pathways other than glycolysis, such as glutamine and fatty acid oxidation, that are key in providing carbon to TC...

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Vydáno v:Neuro Oncol
Hlavní autoři: Kumar, Sushil, Jalali, Shahrzad, Vartanian, Alenoush, Agnihotri, Sameer, Burrell, Kelly, Zadeh, Gelareh
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218620/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou278.10
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