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DOCK8 expression in Treg cells maintains their stability and limits contact hypersensitivity
Chronic dermatitis is a hallmark of Dedicator of cytokinesis 8 (DOCK8) deficiency. The migration of DOCK8-deficient T cells to the skin and their survival there has been reported to be defective. Surprisingly, we found that Dock8(−/−) mice demonstrated an exaggerated contact hypersensitivity (CHS) r...
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| Publicado no: | J Invest Dermatol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8102650/ https://ncbi.nlm.nih.gov/pubmed/33171169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2020.09.027 |
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