Abro1 maintains genome stability and limits replication stress by protecting replication fork stability

Protection of the stalled replication fork is crucial for responding to replication stress and minimizing its impact on chromosome instability, thus preventing diseases, including cancer. We found a new component, Abro1, in the protection of stalled replication fork integrity. Abro1 deficiency resul...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Xu, Shengfeng, Wu, Xiao, Wu, Ling, Castillo, Andy, Liu, Jianxin, Atkinson, Erin, Paul, Atanu, Su, Dan, Schlacher, Katharina, Komatsu, Yoshihiro, You, M. James, Wang, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588928/
https://ncbi.nlm.nih.gov/pubmed/28860160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.299172.117
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