ING2 controls the progression of DNA replication forks to maintain genome stability

Inhibitor of growth 2 (ING2) is a candidate tumour suppressor gene the expression of which is frequently lost in tumours. Here, we identified a new function for ING2 in the control of DNA replication and in the maintenance of genome stability. Global replication rate was markedly reduced during norm...

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Bibliographische Detailangaben
Hauptverfasser: Larrieu, Delphine, Ythier, Damien, Binet, Romuald, Brambilla, Christian, Brambilla, Elisabeth, Sengupta, Sagar, Pedeux, Rémy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
Schlagworte:
Scientific Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759735/
https://ncbi.nlm.nih.gov/pubmed/19730436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.180
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