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Damaged replication forks tolerate USP7 to maintain genome stability

RAD18 functions to promote DNA damage tolerance (DTT), a process that ensures faithful genome duplication. Protein ubiquitylation/deubiquitylation is a critical regulatory mechanism controlling DTT. Recently, we have identified the deubiquitylating enzyme USP7 as a component of the DTT machinery tha...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Zlatanou, Anastasia, Stewart, Grant S.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845244/
https://ncbi.nlm.nih.gov/pubmed/27308573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1063571
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