SMARCAD1-mediated active replication fork stability maintains genome integrity

The stalled fork protection pathway mediated by breast cancer 1/2 (BRCA1/2) proteins is critical for replication fork stability. However, it is unclear whether additional mechanisms are required to maintain replication fork stability. We describe a hitherto unknown mechanism, by which the SWI/SNF-re...

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Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Lo, Calvin Shun Yu, van Toorn, Marvin, Gaggioli, Vincent, Paes Dias, Mariana, Zhu, Yifan, Manolika, Eleni Maria, Zhao, Wei, van der Does, Marit, Mukherjee, Chirantani, G. S. C. Souto Gonçalves, João, van Royen, Martin E., French, Pim J., Demmers, Jeroen, Smal, Ihor, Lans, Hannes, Wheeler, David, Jonkers, Jos, Chaudhuri, Arnab Ray, Marteijn, Jurgen A., Taneja, Nitika
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2021
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099181/
https://ncbi.nlm.nih.gov/pubmed/33952518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe7804
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