SMARCAD1-mediated active replication fork stability maintains genome integrity

The stalled fork protection pathway mediated by breast cancer 1/2 (BRCA1/2) proteins is critical for replication fork stability. However, it is unclear whether additional mechanisms are required to maintain replication fork stability. We describe a hitherto unknown mechanism, by which the SWI/SNF-re...

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Pubblicato in:Sci Adv
Autori principali: Lo, Calvin Shun Yu, van Toorn, Marvin, Gaggioli, Vincent, Paes Dias, Mariana, Zhu, Yifan, Manolika, Eleni Maria, Zhao, Wei, van der Does, Marit, Mukherjee, Chirantani, G. S. C. Souto Gonçalves, João, van Royen, Martin E., French, Pim J., Demmers, Jeroen, Smal, Ihor, Lans, Hannes, Wheeler, David, Jonkers, Jos, Chaudhuri, Arnab Ray, Marteijn, Jurgen A., Taneja, Nitika
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2021
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099181/
https://ncbi.nlm.nih.gov/pubmed/33952518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe7804
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