RIF1 promotes replication fork protection and efficient restart to maintain genome stability

Homologous recombination (HR) and Fanconi Anemia (FA) pathway proteins in addition to their DNA repair functions, limit nuclease-mediated processing of stalled replication forks. However, the mechanism by which replication fork degradation results in genome instability is poorly understood. Here, we...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Mukherjee, Chirantani, Tripathi, Vivek, Manolika, Eleni Maria, Heijink, Anne Margriet, Ricci, Giulia, Merzouk, Sarra, de Boer, H. Rudolf, Demmers, Jeroen, van Vugt, Marcel A. T. M., Ray Chaudhuri, Arnab
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650494/
https://ncbi.nlm.nih.gov/pubmed/31337767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11246-1
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