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DNA damage‐induced replication stress results in PA200‐proteasome‐mediated degradation of acetylated histones

Histone acetylation influences protein interactions and chromatin accessibility and plays an important role in the regulation of transcription, replication, and DNA repair. Conversely, DNA damage affects these crucial cellular processes and induces changes in histone acetylation. However, a comprehe...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Mandemaker, Imke K, Geijer, Marit E, Kik, Iris, Bezstarosti, Karel, Rijkers, Erikjan, Raams, Anja, Janssens, Roel C, Lans, Hannes, Hoeijmakers, Jan HJ, Demmers, Jeroen AA, Vermeulen, Wim, Marteijn, Jurgen A
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172457/
https://ncbi.nlm.nih.gov/pubmed/30104204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201745566
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