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Role for proteasome activator PA200 and postglutamyl proteasome activity in genomic stability
Proteasome activator PA200 enhances proteasome-mediated cleavage after acidic residues in vitro; however, its role within cells is not known. Here, we show that, in response to ionizing radiation, PA200 forms hybrid proteasomes with 19S caps and 20S core proteasomes that accumulate on chromatin, lea...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2570974/ https://ncbi.nlm.nih.gov/pubmed/18845680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803145105 |
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