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Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells

Disruption of the circadian clock machinery in cancer cells is implicated in tumor malignancy. Studies on cancer therapy reveal the presence of heterogeneous cells, including breast cancer stem-like cells (BCSCs), in breast tumors. BCSCs are often characterized by high aldehyde dehydrogenase (ALDH)...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Ogino, Takashi, Matsunaga, Naoya, Tanaka, Takahiro, Tanihara, Tomohito, Terajima, Hideki, Yoshitane, Hikari, Fukada, Yoshitaka, Tsuruta, Akito, Koyanagi, Satoru, Ohdo, Shigehiro
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102063/
https://ncbi.nlm.nih.gov/pubmed/33890571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66155
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