Different Roles of Negative and Positive Components of the Circadian Clock in Oncogene-induced Neoplastic Transformation

In mammals, circadian rhythms in physiological function are generated by a molecular oscillator driven by transcriptional-translational feedback loop consisting of negative and positive regulators. Disruption of this circadian clock machinery is thought to increase the risk of cancer development, bu...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Katamune, Chiharu, Koyanagi, Satoru, Shiromizu, Shoya, Matsunaga, Naoya, Shimba, Shigeki, Shibata, Shigenobu, Ohdo, Shigehiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865904/
https://ncbi.nlm.nih.gov/pubmed/26961881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.706481
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