Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells

Disruption of the circadian clock machinery in cancer cells is implicated in tumor malignancy. Studies on cancer therapy reveal the presence of heterogeneous cells, including breast cancer stem-like cells (BCSCs), in breast tumors. BCSCs are often characterized by high aldehyde dehydrogenase (ALDH)...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Ogino, Takashi, Matsunaga, Naoya, Tanaka, Takahiro, Tanihara, Tomohito, Terajima, Hideki, Yoshitane, Hikari, Fukada, Yoshitaka, Tsuruta, Akito, Koyanagi, Satoru, Ohdo, Shigehiro
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2021
Aiheet:
Cancer Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102063/
https://ncbi.nlm.nih.gov/pubmed/33890571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66155
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