Receptor-type protein tyrosine phosphatase alpha (PTPα) mediates MMP14 localization and facilitates triple-negative breast cancer cell invasion

The ability of cancer cells to invade surrounding tissues requires degradation of the extracellular matrix (ECM). Invasive structures, such as invadopodia, form on the plasma membranes of cancer cells and secrete ECM-degrading proteases that play crucial roles in cancer cell invasion. We have previo...

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Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Decotret, Lisa R., Wadsworth, Brennan J., Li, Ling Vicky, Lim, Chinten J., Bennewith, Kevin L., Pallen, Catherine J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2021
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101463/
https://ncbi.nlm.nih.gov/pubmed/33566639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-01-0060
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