The Interaction of Protein-tyrosine Phosphatase α (PTPα) and RACK1 Protein Enables Insulin-like Growth Factor 1 (IGF-1)-stimulated Abl-dependent and -independent Tyrosine Phosphorylation of PTPα

Protein tyrosine phosphatase α (PTPα) promotes integrin-stimulated cell migration in part through the role of Src-phosphorylated PTPα-Tyr(P)-789 in recruiting and localizing p130Cas to focal adhesions. The growth factor IGF-1 also stimulates PTPα-Tyr-789 phosphorylation to positively regulate cell m...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Khanna, Ranvikram S., Le, Hoa T., Wang, Jing, Fung, Thomas C. H., Pallen, Catherine J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2015
Ämnen:
Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392285/
https://ncbi.nlm.nih.gov/pubmed/25694432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.624247
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