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The Receptor protein tyrosine phosphatase PTP69D antagonizes Abl tyrosine kinase to guide axons in Drosophila

During Drosophila embryogenesis, both the cytoplasmic Abelson tyrosine kinase (Abl) and the membrane bound tyrosine phosphatase PTP69D are required for proper guidance of CNS and motor axons. We provide evidence that PTP69D modulates signaling by Abl and its antagonist, Ena. An Abl loss-of function...

詳細記述

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書誌詳細
主要な著者: Song, Jeong K., Giniger, Edward, Desai, Chand J.
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288561/
https://ncbi.nlm.nih.gov/pubmed/18160268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2007.11.005
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