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Loss of Protein-tyrosine Phosphatase α (PTPα) Increases Proliferation and Delays Maturation of Oligodendrocyte Progenitor Cells

Tightly controlled termination of proliferation determines when oligodendrocyte progenitor cells (OPCs) can initiate differentiation and mature into myelin-forming cells. Protein-tyrosine phosphatase α (PTPα) promotes OPC differentiation, but its role in proliferation is unknown. Here we report that...

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Detalhes bibliográficos
Main Authors: Wang, Pei-Shan, Wang, Jing, Zheng, Yi, Pallen, Catherine J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321002/
https://ncbi.nlm.nih.gov/pubmed/22354965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.312769
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