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Protein-tyrosine Phosphatase α Acts as an Upstream Regulator of Fyn Signaling to Promote Oligodendrocyte Differentiation and Myelination

The tyrosine kinase Fyn plays a key role in oligodendrocyte differentiation and myelination in the central nervous system, but the molecules responsible for regulating Fyn activation in these processes remain poorly defined. Here we show that receptor-like protein-tyrosine phosphatase α (PTPα) is an...

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Autori principali: Wang, Pei-Shan, Wang, Jing, Xiao, Zhi-Cheng, Pallen, Catherine J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785211/
https://ncbi.nlm.nih.gov/pubmed/19812040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.061770
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