Protein Tyrosine Phosphatase Receptor Type Z Negatively Regulates Oligodendrocyte Differentiation and Myelination

BACKGROUND: Fyn tyrosine kinase-mediated down-regulation of Rho activity through activation of p190RhoGAP is crucial for oligodendrocyte differentiation and myelination. Therefore, the loss of function of its counterpart protein tyrosine phosphatase (PTP) may enhance myelination during development a...

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Autors principals: Kuboyama, Kazuya, Fujikawa, Akihiro, Masumura, Makoto, Suzuki, Ryoko, Matsumoto, Masahito, Noda, Masaharu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492236/
https://ncbi.nlm.nih.gov/pubmed/23144976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048797
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