Inactivation of Protein Tyrosine Phosphatase Receptor Type Z by Pleiotrophin Promotes Remyelination through Activation of Differentiation of Oligodendrocyte Precursor Cells

Multiple sclerosis (MS) is a progressive neurological disorder associated with myelin destruction and neurodegeneration. Oligodendrocyte precursor cells (OPCs) present in demyelinated lesions gradually fail to differentiate properly, so remyelination becomes incomplete. Protein tyrosine phosphatase...

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Vydáno v:J Neurosci
Hlavní autoři: Kuboyama, Kazuya, Fujikawa, Akihiro, Suzuki, Ryoko, Noda, Masaharu
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605312/
https://ncbi.nlm.nih.gov/pubmed/26338327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2127-15.2015
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