A head-to-toe dimerization has physiological relevance for ligand-induced inactivation of protein tyrosine receptor type Z

Protein-tyrosine phosphatase (PTPase) receptor type Z (PTPRZ) has two receptor isoforms, PTPRZ-A and -B, containing tandem intracellular PTP-D1 and -D2 domains, with only D1 being active. Pleiotrophin (PTN) binding to the extracellular PTPRZ region leads to inactivation of its PTPase activity, there...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Fujikawa, Akihiro, Sugawara, Hajime, Tanga, Naomi, Ishii, Kentaro, Kuboyama, Kazuya, Uchiyama, Susumu, Suzuki, Ryoko, Noda, Masaharu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791311/
https://ncbi.nlm.nih.gov/pubmed/31416834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007878
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados