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Myosin II and Arp2/3 cross-talk governs intracellular hydraulic pressure and lamellipodia formation
Human fibroblasts can switch between lamellipodia-dependent and -independent migration mechanisms on two-dimensional surfaces and in three-dimensional (3D) matrices. RhoA GTPase activity governs the switch from low-pressure lamellipodia to high-pressure lobopodia in response to the physical structur...
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| Publié dans: | Mol Biol Cell |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Cell Biology
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8101460/ https://ncbi.nlm.nih.gov/pubmed/33502904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-04-0227 |
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