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Myosin II and Arp2/3 cross-talk governs intracellular hydraulic pressure and lamellipodia formation

Human fibroblasts can switch between lamellipodia-dependent and -independent migration mechanisms on two-dimensional surfaces and in three-dimensional (3D) matrices. RhoA GTPase activity governs the switch from low-pressure lamellipodia to high-pressure lobopodia in response to the physical structur...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Patel, Shivani, McKeon, Donna, Sao, Kimheak, Yang, Changsong, Naranjo, Nicole M., Svitkina, Tatyana M., Petrie, Ryan J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101460/
https://ncbi.nlm.nih.gov/pubmed/33502904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-04-0227
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