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Arp2/3 Complex and Actin Depolymerizing Factor/Cofilin in Dendritic Organization and Treadmilling of Actin Filament Array in Lamellipodia

The leading edge (∼1 μm) of lamellipodia in Xenopus laevis keratocytes and fibroblasts was shown to have an extensively branched organization of actin filaments, which we term the dendritic brush. Pointed ends of individual filaments were located at Y-junctions, where the Arp2/3 complex was also loc...

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Détails bibliographiques
Auteurs principaux: Svitkina, Tatyana M., Borisy, Gary G.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2133125/
https://ncbi.nlm.nih.gov/pubmed/10352018
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