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Exo70 Stimulates the Arp2/3 Complex-mediated Actin Branching for Lamellipodia Formation and Cell Migration

Directional cell migration requires the coordination of actin assembly and membrane remodeling. The exocyst is an octameric protein complex essential for exocytosis and plasma membrane remodeling [1,2]. A component of the exocyst, Exo70, directly interacts with the Arp2/3 complex, a core nucleating...

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Autors principals: Liu, Jianglan, Zhao, Yuting, Sun, Yujie, He, Bing, Yang, Changsong, Svitkina, Tatyana, Goldman, Yale E., Guo, Wei
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427469/
https://ncbi.nlm.nih.gov/pubmed/22748316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.05.055
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