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Molecular characterization of HLA class II binding to the LAG‐3 T cell co‐inhibitory receptor

Immune checkpoint inhibitors (antibodies that block the T cell co‐inhibitory receptors PD‐1/PD‐L1 or CTLA‐4) have revolutionized the treatment of some forms of cancer. Importantly, combination approaches using drugs that target both pathways have been shown to boost the efficacy of such treatments....

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: MacLachlan, Bruce J., Mason, Georgina H., Greenshields‐Watson, Alexander, Triebel, Frederic, Gallimore, Awen, Cole, David K., Godkin, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101287/
https://ncbi.nlm.nih.gov/pubmed/32920841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.202048753
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