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Home Sweet Home: The Tumor Microenvironment as a Haven for Regulatory T Cells

CD4(+)Foxp3(+) regulatory T cells (T(regs)) have a fundamental role in maintaining immune balance by preventing autoreactivity and immune-mediated pathology. However this role of T(regs) extends to suppression of anti-tumor immune responses and remains a major obstacle in the development of anti-can...

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Detalhes bibliográficos
Main Authors: Ondondo, Beatrice, Jones, Emma, Godkin, Andrew, Gallimore, Awen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712544/
https://ncbi.nlm.nih.gov/pubmed/23874342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00197
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