T Cell Trafficking Facilitated by High Endothelial Venules is Required for Tumor Control after Regulatory T Cell Depletion

The evolution of immune blockades in tumors limits successful anti-tumor immunity, but the mechanisms underlying this process are not fully understood. Depletion of regulatory T cells (Tregs), a T cell subset that dampens excessive inflammatory and autoreactive responses, can allow activation of tum...

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Bibliographic Details
Main Authors: Hindley, James P., Jones, Emma, Smart, Kathryn, Bridgeman, Hayley, Lauder, Sarah N., Ondondo, Beatrice, Cutting, Scott, Ladell, Kristin, Wynn, Katherine K., Withers, David, Price, David A., Ager, Ann, Godkin, Andrew J., Gallimore, Awen M.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491872/
https://ncbi.nlm.nih.gov/pubmed/22962270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1912
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