T Cell Trafficking Facilitated by High Endothelial Venules is Required for Tumor Control after Regulatory T Cell Depletion

The evolution of immune blockades in tumors limits successful anti-tumor immunity, but the mechanisms underlying this process are not fully understood. Depletion of regulatory T cells (Tregs), a T cell subset that dampens excessive inflammatory and autoreactive responses, can allow activation of tum...

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Bibliografiske detaljer
Main Authors: Hindley, James P., Jones, Emma, Smart, Kathryn, Bridgeman, Hayley, Lauder, Sarah N., Ondondo, Beatrice, Cutting, Scott, Ladell, Kristin, Wynn, Katherine K., Withers, David, Price, David A., Ager, Ann, Godkin, Andrew J., Gallimore, Awen M.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491872/
https://ncbi.nlm.nih.gov/pubmed/22962270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1912
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