T Cell Trafficking Facilitated by High Endothelial Venules is Required for Tumor Control after Regulatory T Cell Depletion

The evolution of immune blockades in tumors limits successful anti-tumor immunity, but the mechanisms underlying this process are not fully understood. Depletion of regulatory T cells (Tregs), a T cell subset that dampens excessive inflammatory and autoreactive responses, can allow activation of tum...

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Main Authors: Hindley, James P., Jones, Emma, Smart, Kathryn, Bridgeman, Hayley, Lauder, Sarah N., Ondondo, Beatrice, Cutting, Scott, Ladell, Kristin, Wynn, Katherine K., Withers, David, Price, David A., Ager, Ann, Godkin, Andrew J., Gallimore, Awen M.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491872/
https://ncbi.nlm.nih.gov/pubmed/22962270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1912
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