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Overexpression of TNFα induces senescence, autophagy and mitochondrial dysfunctions in melanoma cells

BACKGROUND: Tumor necrosis factor alpha (TNFα) is a pleiotropic cytokine with both anti-tumorigenic and pro-tumorigenic activity, affecting tumor cell biology, the balance between cell survival and death. The final effect of TNFα is dependent on the type of malignant cells, with the potential to arr...

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Publicat a:BMC Cancer
Autors principals: Tyciakova, Silvia, Valova, Valeria, Svitkova, Barbora, Matuskova, Miroslava
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101174/
https://ncbi.nlm.nih.gov/pubmed/33957885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-08237-1
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