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Overexpression of TNFα induces senescence, autophagy and mitochondrial dysfunctions in melanoma cells
BACKGROUND: Tumor necrosis factor alpha (TNFα) is a pleiotropic cytokine with both anti-tumorigenic and pro-tumorigenic activity, affecting tumor cell biology, the balance between cell survival and death. The final effect of TNFα is dependent on the type of malignant cells, with the potential to arr...
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| Опубликовано в: : | BMC Cancer |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8101174/ https://ncbi.nlm.nih.gov/pubmed/33957885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-08237-1 |
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