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TNF-α and Beyond: Rapid Mitochondrial Dysfunction Mediates TNF-α-Induced Neurotoxicity

This short communication describes our research which demonstrates that TNF-α causes a rapid decline in mitochondrial function, leading to neuronal cell death. As such, this neurotoxic proinflammatory cytokine may play a role in brain damage from stroke and neurodegeneration in chronic conditions su...

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Detalhes bibliográficos
Publicado no:J Clin Cell Immunol
Main Authors: Russell, Ashley E., Doll, Danielle N., Sarkar, Saumyendra N., Simpkins, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482413/
https://ncbi.nlm.nih.gov/pubmed/28652929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9899.1000467
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