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Rapid mitochondrial dysfunction mediates TNF-alpha-induced neurotoxicity
Tumor necrosis factor alpha (TNF-α) is known to exacerbate ischemic brain injury; however, the mechanism is unknown. Previous studies have evaluated the effects of TNF-α on neurons with long exposures to high doses of TNF-α, which is not pathophysiologically relevant. We characterized the rapid effe...
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| Yayımlandı: | J Neurochem |
|---|---|
| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4459129/ https://ncbi.nlm.nih.gov/pubmed/25492727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13008 |
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