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Uncoupling of the Electron Transport Chain Compromises Mitochondrial Oxidative Phosphorylation and Exacerbates Stroke Outcomes

OBJECTIVE: Mitochondrial dysfunction is known to be implicated in stroke, but the complex mechanisms of stroke have led to few stroke therapies. The present study to disrupted mitochondrial oxidative phosphorylation through a known electron transport chain (ETC) uncoupler, Carbonyl cyanide-4 (triflu...

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Detalhes bibliográficos
Publicado no:J Neuroinfect Dis
Main Authors: Grasmick, Kimberly A, Hu, Heng, Hone, Emily A, Farooqi, Imran, Rellick, Stephanie L, Simpkins, James W, Ren, Xuefang
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059652/
https://ncbi.nlm.nih.gov/pubmed/32149160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2314-7326.1000283
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