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Estrogen amelioration of Aβ-induced defects in mitochondria is mediated by mitochondrial signaling pathway involving ERβ, AKAP and Drp1
Perturbations in dynamic properties of mitochondria including fission, fusion, and movement lead to disruption of energy supply to synapses contributing to neuropathology and cognitive dysfunction in Alzheimer’s disease (AD). The molecular mechanisms underlying these defects are still unclear. Previ...
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| Veröffentlicht in: | Brain Res |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4464937/ https://ncbi.nlm.nih.gov/pubmed/25964165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2015.04.059 |
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