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Estrogen amelioration of Aβ-induced defects in mitochondria is mediated by mitochondrial signaling pathway involving ERβ, AKAP and Drp1

Perturbations in dynamic properties of mitochondria including fission, fusion, and movement lead to disruption of energy supply to synapses contributing to neuropathology and cognitive dysfunction in Alzheimer’s disease (AD). The molecular mechanisms underlying these defects are still unclear. Previ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Brain Res
Hauptverfasser: Sarkar, Saumyendra, Jun, Sujung, Simpkins, James W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464937/
https://ncbi.nlm.nih.gov/pubmed/25964165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2015.04.059
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