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Autophagy suppresses melanoma tumorigenesis by inducing senescence

Whether and how autophagy is involved in tumorigenesis is poorly understood. We approached this question by investigating a relatively large cohort of patients with mostly early primary melanoma for their expression of 2 markers for autophagy, the protein ATG5 (autophagy-related 5) and MAP1LC3B/LC3...

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Publicat a:Autophagy
Autors principals: Liu, He, He, Zhaoyue, Simon, Hans-Uwe
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396100/
https://ncbi.nlm.nih.gov/pubmed/24300435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.27163
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