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PERK-ing up autophagy during MYC-induced tumorigenesis

Stress in the tumor microenvironment in the form of hypoxia and low glucose/amino acid levels activates the evolutionarily conserved cellular adaptation program called the unfolded protein response (UPR) promoting cell survival in such conditions. Our recent studies showed that cell autonomous stres...

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Hlavní autoři: Dey, Souvik, Tameire, Feven, Koumenis, Constantinos
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627677/
https://ncbi.nlm.nih.gov/pubmed/23328692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23486
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