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PERK-ing up autophagy during MYC-induced tumorigenesis
Stress in the tumor microenvironment in the form of hypoxia and low glucose/amino acid levels activates the evolutionarily conserved cellular adaptation program called the unfolded protein response (UPR) promoting cell survival in such conditions. Our recent studies showed that cell autonomous stres...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627677/ https://ncbi.nlm.nih.gov/pubmed/23328692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23486 |
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