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Autophagy suppresses melanoma tumorigenesis by inducing senescence

Whether and how autophagy is involved in tumorigenesis is poorly understood. We approached this question by investigating a relatively large cohort of patients with mostly early primary melanoma for their expression of 2 markers for autophagy, the protein ATG5 (autophagy-related 5) and MAP1LC3B/LC3...

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Detalles Bibliográficos
Publicado en:Autophagy
Main Authors: Liu, He, He, Zhaoyue, Simon, Hans-Uwe
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396100/
https://ncbi.nlm.nih.gov/pubmed/24300435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.27163
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